bio-list

Sero-conversion Examine for a Two-dose Schedule of Sabin IPV in China

In April 2017, WHO/SAGE beneficial {that a} two-dose, IPV-only schedule can be utilized after polio eradication, with a schedule seroconversion goal of no less than 90%.

The suggestion was primarily based partly on a examine performed in Cuba utilizing Salk-IPV at Four months and eight months of age.

Nonetheless, for home Sabin IPVs, there aren’t any such information to help a 2-dose schedule amongst Chinese language infants.Two Sabin IPV merchandise which might be out there to China’s Nationwide Immunization Program – produced by Kunming Bio institute and China Nationwide Biotec Group (CNBG).

The monitoring examine on sIPV produced by Kunming Bio institute has already utilized for approval.

This examine goals to acquire the direct home IPVvaccine monitoring information for the CNBG merchandise, and supply scientific proof for the Nationwide Immunization Program and long-term polio vaccine immunization coverage.

The total goal of this analysis is to find out the seroconversion charges of two decreased Sabin IPV schedules in Chinese language kids – a 2-dose schedule and a 3-dose schedule.

The particular aims of the examine are to:

1. Decide whether or not the seroconversion fee is above 90% with a 2-dose Sabin IPV schedule, with the primary dose given at 4 months and the second dose given ≥Four months after the primary dose.

2. Measure neutralizing antibody titers towards poliovirus kind I, II and III amongst two-dose Sabin IPV alone schedule, in contrast with three-dose Sabin IPV alone schedule.

bio-list
bio-list

Anti-Hu CD193 Pacific Blue

PB-161-T100 100 tests
EUR 269

Anti-Hu CD3 Pacific Blue

PB-202-T025 25 tests
EUR 154

Anti-Hu CD3 Pacific Blue

PB-202-T100 100 tests
EUR 269

Anti-Hu CD6 Pacific Blue

PB-205-T025 25 tests
EUR 154

Anti-Hu CD6 Pacific Blue

PB-205-T100 100 tests
EUR 269

Anti-Hu CD7 Pacific Blue

PB-206-T025 25 tests
EUR 154

Anti-Hu CD7 Pacific Blue

PB-206-T100 100 tests
EUR 269

Anti-Hu CD8 Pacific Blue

PB-207-T025 25 tests
EUR 154

Anti-Hu CD8 Pacific Blue

PB-207-T100 100 tests
EUR 269

Anti-Hu CD9 Pacific Blue

PB-208-T025 25 tests
EUR 154

Anti-Hu CD9 Pacific Blue

PB-208-T100 100 tests
EUR 269

Anti-Hu CD10 Pacific Blue

PB-209-T025 25 tests
EUR 154

Anti-Hu CD10 Pacific Blue

PB-209-T100 100 tests
EUR 269

Anti-Hu CD15 Pacific Blue

PB-213-T025 25 tests
EUR 154

Anti-Hu CD15 Pacific Blue

PB-213-T100 100 tests
EUR 269

Anti-Hu CD25 Pacific Blue

PB-218-T025 25 tests
EUR 154

Anti-Hu CD25 Pacific Blue

PB-218-T100 100 tests
EUR 269

Anti-Hu CD29 Pacific Blue

PB-219-T025 25 tests
EUR 154

Anti-Hu CD29 Pacific Blue

PB-219-T100 100 tests
EUR 269

Anti-Hu CD43 Pacific Blue

PB-220-T025 25 tests
EUR 154

Anti-Hu CD43 Pacific Blue

PB-220-T100 100 tests
EUR 269

Anti-Hu CD44 Pacific Blue

PB-221-T025 25 tests
EUR 154

Anti-Hu CD44 Pacific Blue

PB-221-T100 100 tests
EUR 269

Anti-Hu CD45 Pacific Blue

PB-222-T025 25 tests
EUR 154

Anti-Hu CD45 Pacific Blue

PB-222-T100 100 tests
EUR 269

Anti-Hu CD45RA Pacific Blue

PB-223-T025 25 tests
EUR 154

Anti-Hu CD45RA Pacific Blue

PB-223-T100 100 tests
EUR 269

Anti-Hu CD47 Pacific Blue

PB-225-T025 25 tests
EUR 154

Anti-Hu CD47 Pacific Blue

PB-225-T100 100 tests
EUR 269

Anti-Hu CD48 Pacific Blue

PB-226-T025 25 tests
EUR 154

Anti-Hu CD48 Pacific Blue

PB-226-T100 100 tests
EUR 269

Anti-Hu CD53 Pacific Blue

PB-227-T025 25 tests
EUR 154

Anti-Hu CD53 Pacific Blue

PB-227-T100 100 tests
EUR 269

Anti-Hu CD59 Pacific Blue

PB-233-T025 25 tests
EUR 154

Anti-Hu CD59 Pacific Blue

PB-233-T100 100 tests
EUR 269

Anti-Hu CD71 Pacific Blue

PB-235-T025 25 tests
EUR 154

Anti-Hu CD71 Pacific Blue

PB-235-T100 100 tests
EUR 269

Anti-Hu CD31 Pacific Blue

PB-273-T025 25 tests
EUR 154

Anti-Hu CD31 Pacific Blue

PB-273-T100 100 tests
EUR 269

Anti-Hu CD80 Pacific Blue

PB-287-T025 25 tests
EUR 154

Anti-Hu CD80 Pacific Blue

PB-287-T100 100 tests
EUR 269

Anti-Hu CD14 Pacific Blue

PB-293-T025 25 tests
EUR 154

Anti-Hu CD14 Pacific Blue

PB-293-T100 100 tests
EUR 269

Anti-Hu CD34 Pacific Blue

PB-297-T025 25 tests
EUR 154

Anti-Hu CD34 Pacific Blue

PB-297-T100 100 tests
EUR 269

Anti-Hu CD105 Pacific Blue

PB-298-T025 25 tests
EUR 154

Anti-Hu CD105 Pacific Blue

PB-298-T100 100 tests
EUR 269

Anti-Hu CD19 Pacific Blue

PB-305-T025 25 tests
EUR 154

Anti-Hu CD19 Pacific Blue

PB-305-T100 100 tests
EUR 269

Anti-Hu CD21 Pacific Blue

PB-306-T025 25 tests
EUR 154

Anti-Hu CD21 Pacific Blue

PB-306-T100 100 tests
EUR 269

Anti-Hu CD27 Pacific Blue

PB-308-T025 25 tests
EUR 154

Anti-Hu CD27 Pacific Blue

PB-308-T100 100 tests
EUR 269

Anti-Hu CD41 Pacific Blue

PB-309-T025 25 tests
EUR 154

Anti-Hu CD41 Pacific Blue

PB-309-T100 100 tests
EUR 269

Anti-Hu CD177 Pacific Blue

PB-314-T025 25 tests
EUR 154

Anti-Hu CD177 Pacific Blue

PB-314-T100 100 tests
EUR 269

Anti-Hu IgM Pacific Blue

PB-320-C100 0.1 mg
EUR 238

Anti-Hu CD46 Pacific Blue

PB-342-T025 25 tests
EUR 154

Anti-Hu CD46 Pacific Blue

PB-342-T100 100 tests
EUR 269

Anti-Hu CD4 Pacific Blue

PB-359-T025 25 tests
EUR 154

Anti-Hu CD4 Pacific Blue

PB-359-T100 100 tests
EUR 269

Anti-Hu CD33 Pacific Blue

PB-365-T025 25 tests
EUR 154

Anti-Hu CD33 Pacific Blue

PB-365-T100 100 tests
EUR 269

Anti-Hu CD38 Pacific Blue

PB-366-T025 25 tests
EUR 154

Anti-Hu CD38 Pacific Blue

PB-366-T100 100 tests
EUR 269

Anti-Hu CD52 Pacific Blue

PB-368-T025 25 tests
EUR 154

Anti-Hu CD52 Pacific Blue

PB-368-T100 100 tests
EUR 269

Anti-Hu CD20 Pacific Blue

PB-414-T025 25 tests
EUR 154

Anti-Hu CD20 Pacific Blue

PB-414-T100 100 tests
EUR 269

Anti-Hu CD41a Pacific Blue

PB-417-T100 100 tests
EUR 269

Anti-HLA-DR Pacific Blue

PB-474-T025 25 tests
EUR 154

Anti-HLA-DR Pacific Blue

PB-474-T100 100 tests
EUR 269

Anti-Hu CD5 Pacific Blue

PB-482-T025 25 tests
EUR 154

Anti-Hu CD5 Pacific Blue

PB-482-T100 100 tests
EUR 269

Anti-Hu CD2 Pacific Blue

PB-492-T025 25 tests
EUR 154

Anti-Hu CD2 Pacific Blue

PB-492-T100 100 tests
EUR 269

Anti-Hu CD24 Pacific Blue

PB-503-T025 25 tests
EUR 154

Anti-Hu CD24 Pacific Blue

PB-503-T100 100 tests
EUR 269

Anti-Hu CD22 Pacific Blue

PB-506-T025 25 tests
EUR 154

Anti-Hu CD22 Pacific Blue

PB-506-T100 100 tests
EUR 269

Anti-Hu CD3 Pacific Blue

PB-514-T025 25 tests
EUR 154

Anti-Hu CD3 Pacific Blue

PB-514-T100 100 tests
EUR 269

Anti-Hu CD11c Pacific Blue

PB-529-T025 25 tests
EUR 154

Anti-Hu CD11c Pacific Blue

PB-529-T100 100 tests
EUR 269

Anti-Hu CD81 Pacific Blue

PB-558-T100 100 tests
EUR 269

Anti-Hu CD28 Pacific Blue

PB-577-T025 25 tests
EUR 154

Anti-Hu CD28 Pacific Blue

PB-577-T100 100 tests
EUR 269

Anti-Ms CD8a Pacific Blue

PB-579-C025 0.025 mg
EUR 139

 

MB-CART19.1 in Sufferers With R/R ALL

That is an open-label, non-randomized part II paediatric examine. On this examine, eligible sufferers will obtain autologous T cells transduced with the lentiviral vector pLTG1563 (MB-CART19.1) at a doesage of 2x10e6 ~2x10e7 CAR-transduced T cells/kg.

Upon enrollment, leukapheresis shall be carried out for MB-CART19.1 technology.

Sufferers with excessive illness burden at screening (e.g. ALL with M3 marrow and 10.000/L blasts in peripheral blood) might obtain bridging chemotherapy after leukapheresis, to keep away from crucial tumor lysis syndrome and cytokine launch syndrome (CRS) by subsequent lymphodepleting chemotherapy and CAR switch.

All sufferers will obtain lymphodepleting chemotherapy with fludarabine 30 mg/m2/d intravenously (iv) on days -5,-4,-Three and -2 cyclophosphamide 500 mg/m2/d iv on day -3,-2 earlier than CAR T cell switch to reinforce the in vivo growth of CAR T cells.

Sufferers will obtain freshly ready MB-CART19.1 on day 0, similar to day 12 (48 hours) of producing, at a dose of 2x10e6 ~2x10e7/kg MB-CART19.1 T cells as outlined within the examine design part.

The acceptable quantity for the goal cell dose shall be drawn up and given as an IV injection over 30 minutes by way of a big vein peripherally or centrally.

The first aims are:

– To evaluate the protection and tolerability of MB-CART19.1.

– To judge the organic exercise of adoptive switch of autologous MB-CART19.1 in sufferers with R/R CD19-positive B cell lymphoblastic leukemia.

The first endpoint is Total response fee (ORR):ORR in ALL sufferers is outlined as the speed of full remission (CR, CRh) on day 28.

Bioequivalence Examine of Cyclosporine 100mg Capsule Below Fasting Situation

 

Complete 36 regular wholesome grownup male topics shall be enrolled within the examine.

Topics shall be administered both the Take a look at or the Reference Product with 240 mL of water in every interval as per the randomization schedule.

Topics will quick for no less than 10 hours previous to dose administration and for no less than Four hours publish dose.

Standardized meals shall be supplied in every examine interval. Water is not going to be accessible to the themes 1 hour Predose and a pair of hours Publish dose in every interval.

A complete of 24 blood samples shall be withdrawn for pharmacokinetic profiling.

The entire blood concentrations of Cyclosporine shall be measured by a validated LC/MS/MS analytical methodology.

Ratio evaluation shall be carried out for untransformed and log remodeled pharmacokinetic parameters Cmax, AUC0-72, AUC0 inf.

ANOVA shall be carried out on log remodeled pharmacokinetic parameters Cmax, AUC0-72, AUC0-inf and 90% confidence interval shall be constructed for the ratio of geometric least sq. imply of the Take a look at and Reference merchandise, obtained from the log-transformed information.

 

Bioequivalence shall be concluded if the ratio estimate in addition to its 90% confidence interval, each falls throughout the acceptable vary of 80.00% to 125.00% for Cmax, AUC0-72 and AUC0-info.

 

 

Alpha-bungarotoxin CF488a

9-00005
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF568

9-00006
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin, CF568

9-00006
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF594

9-00007
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin CF594

9-00007
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF633

9-00009
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 500uG

Alpha-bungarotoxin, CF633

9-00009
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100uG
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin

00010-1 1MG
EUR 168
Description: Minimum order quantity: 1 unit of 1MG

Fluorescein-Alpha-bungarotoxin

00011 500uG
EUR 367
Description: Minimum order quantity: 1 unit of 500uG

Tetramethylrhodamine-Alpha-bungarotoxin

00012 500uG
EUR 383
Description: Minimum order quantity: 1 unit of 500uG

Fluorescein-alpha-bungarotoxin: (10x50ug)

00013 10ST
EUR 417
Description: Minimum order quantity: 1 unit of 10ST

Tetramethylrhodamine-alpha-bungarotoxin: (10x50ug)

00014 10ST
EUR 466
Description: Minimum order quantity: 1 unit of 10ST

Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (500ug)

00015 500uG
EUR 466
Description: Minimum order quantity: 1 unit of 500uG

Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (10x50ug)

00016 10ST
EUR 523
Description: Minimum order quantity: 1 unit of 10ST

Biotin-xx-a-bungarotoxin

00017 500uG
EUR 433
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF555 conjugate

9-00018
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100ug
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF555 conjugate

9-00018
  • EUR 494.00
  • EUR 161.00
  • 500uG
  • 100ug
Description: Minimum order quantity: 1 unit of 100ug

Biotin-cAMP, diisopropylethylammonium salt:

00020 1MG
EUR 314
Description: Minimum order quantity: 1 unit of 1MG

Biotin-cAMP, diisopropylethylammonium salt: (20x50ug)

00020-1 20ST
EUR 418
Description: Minimum order quantity: 1 unit of 20ST

Biotin-cGMP, diisopropylethylammonium salt:

00021 1MG
EUR 344
Description: Minimum order quantity: 1 unit of 1MG

Biotin-cGMP, diisopropylethylammonium salt: (20x50ug)

00021-1 20ST
EUR 448
Description: Minimum order quantity: 1 unit of 20ST

Cyanine 644-cAMP:

00022 1MG
EUR 491
Description: Minimum order quantity: 1 unit of 1MG

Cyanine 644-cAMP: (20x50ug)

00022-1 20ST
EUR 625
Description: Minimum order quantity: 1 unit of 20ST

Fluorescein Methotrexate, triammonium salt:

00023 1MG
EUR 281
Description: Minimum order quantity: 1 unit of 1MG

Staurosporine

00025 100uG
EUR 139
Description: Minimum order quantity: 1 unit of 100uG

Alpha-bungarotoxin, CF543

00026 500uG
EUR 494
Description: Minimum order quantity: 1 unit of 500uG

Rhodamine phalloidin 300u

00027 300
EUR 345
Description: Minimum order quantity: 1 unit of 300

Biotin-xx-phalloidin

00028 100U
EUR 428
Description: Minimum order quantity: 1 unit of 100U

Fluorescein-phalloidin

00030 300U
EUR 345
Description: Minimum order quantity: 1 unit of 300U

Rhodamine 110 phalloidin

00032 300ST
EUR 345
Description: Minimum order quantity: 1 unit of 300ST

Sulforhodamine 101 (Texas-Red) Phalloidin

00033 300EU
EUR 345
Description: Minimum order quantity: 1 unit of 300EU

Phalloidin, CF405M

00034 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF405M

00034-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

CF488A-cAMP

00036 100ug
EUR 172
Description: Minimum order quantity: 1 unit of 100ug

CF640R-cAMP

00037 100ug
EUR 172
Description: Minimum order quantity: 1 unit of 100ug

Phalloidin, CF555

00040 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF555

00040-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF647

00041 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF647

00041-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF488A

00042 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF488A

00042-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF543

00043 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF543

00043-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF568

00044 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF568

00044-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF594

00045 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF594

00045-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF633

00046 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF633

00046-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF660R

00047 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF660R

00047-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF680R

00048 300U
EUR 466
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF680R

00048-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF350

00049 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF350

00049-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF640R

00050 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF640R

00050-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF532

00051 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF532

00051-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF660C

00052 300U
EUR 442
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF660C

00052-T 50U
EUR 133
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF680

00053 300U
EUR 466
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF680

00053-T 50U
EUR 147
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF430

00054 300U
EUR 449
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF430

00054-T 50U
EUR 139
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF440

00055 300U
EUR 449
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF440

00055-T 50U
EUR 139
Description: Minimum order quantity: 1 unit of 50U

Cholera Toxin Subunit B, CF488A conjugate

00070 100ug
EUR 261
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF568 conjugate

00071 100ug
EUR 261
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF594 conjugate

00072 100ug
EUR 261
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF640R conjugate

00073 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF532 conjugate

00074 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF543 conjugate

00075 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF620R conjugate

00076 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF633 conjugate

00077 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF660R conjugate

00078 100ug
EUR 264
Description: Minimum order quantity: 1 unit of 100ug

Cholera Toxin Subunit B, CF680R conjugate

00079 100ug
EUR 282
Description: Minimum order quantity: 1 unit of 100ug

Human Transferrin, CF488A conjugate

00081 1mg
EUR 149
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF543 conjugate

00082 1mg
EUR 149
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF568 conjugate

00083 1mg
EUR 149
Description: Minimum order quantity: 1 unit of 1mg

Human Transferrin, CF594 conjugate

00084 1mg
EUR 149
Description: Minimum order quantity: 1 unit of 1mg



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