bio-list

Sero-conversion Examine for a Two-dose Schedule of Sabin IPV in China

In April 2017, WHO/SAGE beneficial {that a} two-dose, IPV-only schedule can be utilized after polio eradication, with a schedule seroconversion goal of no less than 90%.

The suggestion was primarily based partly on a examine performed in Cuba utilizing Salk-IPV at Four months and eight months of age.

Nonetheless, for home Sabin IPVs, there aren’t any such information to help a 2-dose schedule amongst Chinese language infants.Two Sabin IPV merchandise which might be out there to China’s Nationwide Immunization Program – produced by Kunming Bio institute and China Nationwide Biotec Group (CNBG).

The monitoring examine on sIPV produced by Kunming Bio institute has already utilized for approval.

This examine goals to acquire the direct home IPVvaccine monitoring information for the CNBG merchandise, and supply scientific proof for the Nationwide Immunization Program and long-term polio vaccine immunization coverage.

The total goal of this analysis is to find out the seroconversion charges of two decreased Sabin IPV schedules in Chinese language kids – a 2-dose schedule and a 3-dose schedule.

The particular aims of the examine are to:

1. Decide whether or not the seroconversion fee is above 90% with a 2-dose Sabin IPV schedule, with the primary dose given at 4 months and the second dose given ≥Four months after the primary dose.

2. Measure neutralizing antibody titers towards poliovirus kind I, II and III amongst two-dose Sabin IPV alone schedule, in contrast with three-dose Sabin IPV alone schedule.

bio-list
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Hydroxynaphthol blue

GT3182-100 100
EUR 205.7

Hydroxynaphthol blue

GT3182-25 25
EUR 79.1

Hydroxynaphthol blue

GT3182-50 50
EUR 134.4

Hydroxynapthol Blue, ACS

25000-25 25g
EUR 43
Description: 165660-27-5

Hydroxy naphthol blue disodium salt

GT4927-100G 100 g
EUR 122.4

Hydroxy naphthol blue disodium salt

GT4927-25G 25 g
EUR 74.4

Hydroxy naphthol blue disodium salt

GT4927-100 100
EUR 71.1

Hydroxy naphthol blue disodium salt

GT4927-25 25
EUR 31.7

DURAN Hydra Square GL45 Purging Bottle Clear 1000mL with 4x GL45 Side Necks

BOT2570 EACH
EUR 351.6

ECOS Blue (XL1-Blue

FYE107-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE107-80VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE108-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE108-80VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE109-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE109-80VL 100 µl x 10 vials Ask for price

Snap Cap 11mm Blue Si/ PTFE Blue

CHR3550 PK1000
EUR 1298.4

Snap Cap 11mm Blue Si/PTFE Blue

CHR3552 PK1000
EUR 561.6

Luxol Fast Blue ARN (Solvent Blue 37)

L05250 25G
EUR 377.63

Container 125ml PP Blue+Label+Blue Cap

CON1013 PK380
EUR 241.2

Dextran blue 2000

20-abx082076
  • EUR 260.40
  • EUR 427.20
  • 1 g
  • 5 g

Flat Cap with Lip Seal Blue

T340BLSFT PK1000
EUR 111.6

Acid Blue 120

T19878-10mg 10mg Ask for price
Description: Acid Blue 120

Acid Blue 120

T19878-1g 1g Ask for price
Description: Acid Blue 120

Acid Blue 120

T19878-1mg 1mg Ask for price
Description: Acid Blue 120

Acid Blue 120

T19878-50mg 50mg Ask for price
Description: Acid Blue 120

Acid Blue 120

T19878-5mg 5mg Ask for price
Description: Acid Blue 120

Blue Gal

21530091-1 500 mg
EUR 114.99

Blue Gal

21530091-2 1 g
EUR 184.61

Blue Gal

21530091-3 100 mg
EUR 59.09

True Blue

574277 5.0mg
EUR 595

Fast Blue

17740-1 1mg
EUR 160
Description: 74749-42-1

Fast Blue

17740-5 5mg
EUR 452
Description: 74749-42-1

True Blue

T37667-10mg 10mg Ask for price
Description: True Blue

True Blue

T37667-1g 1g Ask for price
Description: True Blue

True Blue

T37667-1mg 1mg Ask for price
Description: True Blue

True Blue

T37667-50mg 50mg Ask for price
Description: True Blue

True Blue

T37667-5mg 5mg Ask for price
Description: True Blue

Albumin blue 670

T29837-10mg 10mg Ask for price
Description: Albumin blue 670

Albumin blue 670

T29837-1g 1g Ask for price
Description: Albumin blue 670

Albumin blue 670

T29837-1mg 1mg Ask for price
Description: Albumin blue 670

Albumin blue 670

T29837-50mg 50mg Ask for price
Description: Albumin blue 670

Albumin blue 670

T29837-5mg 5mg Ask for price
Description: Albumin blue 670

Evans Blue

abx186080-125g 125g
EUR 543.6

Evans Blue

20-abx082082
  • EUR 210.00
  • EUR 260.40
  • 1 g
  • 5 g

Evans Blue

20-abx082237
  • EUR 226.80
  • EUR 276.00
  • 1 g
  • 5 g

Evans Blue

HY-B1102 100mg
EUR 142.8

Evans Blue

09158-74 5G
EUR 34.3

Janus blue

596109 25.0g
EUR 320

EVANS BLUE

E2799 100G
EUR 69.82

Owens Blue

O03540 5G
EUR 211.74

Astra Blue

GT8099-25 25
EUR 118.7

Astra Blue

GT8099-5 5
EUR 31.7

Evans Blue

40140055-1 10 g
EUR 37.07

Evans blue

T0313-10mg 10mg Ask for price
Description: Evans blue

Evans blue

T0313-1g 1g Ask for price
Description: Evans blue

Evans blue

T0313-1mg 1mg Ask for price
Description: Evans blue

Evans blue

T0313-50mg 50mg Ask for price
Description: Evans blue

Evans blue

T0313-5mg 5mg Ask for price
Description: Evans blue

Janus blue

T32263-10mg 10mg Ask for price
Description: Janus blue

Janus blue

T32263-1g 1g Ask for price
Description: Janus blue

Janus blue

T32263-1mg 1mg Ask for price
Description: Janus blue

Janus blue

T32263-50mg 50mg Ask for price
Description: Janus blue

Janus blue

T32263-5mg 5mg Ask for price
Description: Janus blue

BLUE-GAL

X884 100MG
EUR 114.96

Disperse Blue 124

LCS-4848 EACH
EUR 388.8

Disperse Blue 148

HY-D0569 10mM/1mL
EUR 206.4

Disperse Blue 148

T18980-10mg 10mg Ask for price
Description: Disperse Blue 148

Disperse Blue 148

T18980-1g 1g Ask for price
Description: Disperse Blue 148

Disperse Blue 148

T18980-1mg 1mg Ask for price
Description: Disperse Blue 148

Disperse Blue 148

T18980-50mg 50mg Ask for price
Description: Disperse Blue 148

Disperse Blue 148

T18980-5mg 5mg Ask for price
Description: Disperse Blue 148

Trypan Blue

20-abx082476
  • EUR 276.00
  • EUR 226.80
  • 25 g
  • 5 g

Thymol Blue

GT9755-100G 100 g
EUR 180

Thymol Blue

GT9755-10G 10 g
EUR 60

Thymol Blue

GT9755-25G 25 g
EUR 84

Thymol Blue

GT9755-50G 50 g
EUR 112.8

Thymol Blue

GT9755-5G 5 g
EUR 50.4

Thymol blue

464075 10.0mg Ask for price

Thymol Blue

33908-52 25G
EUR 45.5

Thymol Blue

33908-81 1G
EUR 21

ALCIAN BLUE

A1286 100G
EUR 92.65

Trypan blue

TT1140 10g
EUR 78.79

Phenol Blue

P06900 1G
EUR 314.21

Thymol Blue

GT9755-10 10
EUR 19.8

Thymol Blue

GT9755-100 100
EUR 118.7

Thymol Blue

GT9755-25 25
EUR 39.4

Thymol Blue

GT9755-5 5
EUR 13

Thymol Blue

GT9755-50 50
EUR 63.3

Thymol Blue

42040000-1 5 g
EUR 24.71

 

MB-CART19.1 in Sufferers With R/R ALL

That is an open-label, non-randomized part II paediatric examine. On this examine, eligible sufferers will obtain autologous T cells transduced with the lentiviral vector pLTG1563 (MB-CART19.1) at a doesage of 2x10e6 ~2x10e7 CAR-transduced T cells/kg.

Upon enrollment, leukapheresis shall be carried out for MB-CART19.1 technology.

Sufferers with excessive illness burden at screening (e.g. ALL with M3 marrow and 10.000/L blasts in peripheral blood) might obtain bridging chemotherapy after leukapheresis, to keep away from crucial tumor lysis syndrome and cytokine launch syndrome (CRS) by subsequent lymphodepleting chemotherapy and CAR switch.

All sufferers will obtain lymphodepleting chemotherapy with fludarabine 30 mg/m2/d intravenously (iv) on days -5,-4,-Three and -2 cyclophosphamide 500 mg/m2/d iv on day -3,-2 earlier than CAR T cell switch to reinforce the in vivo growth of CAR T cells.

Sufferers will obtain freshly ready MB-CART19.1 on day 0, similar to day 12 (48 hours) of producing, at a dose of 2x10e6 ~2x10e7/kg MB-CART19.1 T cells as outlined within the examine design part.

The acceptable quantity for the goal cell dose shall be drawn up and given as an IV injection over 30 minutes by way of a big vein peripherally or centrally.

The first aims are:

– To evaluate the protection and tolerability of MB-CART19.1.

– To judge the organic exercise of adoptive switch of autologous MB-CART19.1 in sufferers with R/R CD19-positive B cell lymphoblastic leukemia.

The first endpoint is Total response fee (ORR):ORR in ALL sufferers is outlined as the speed of full remission (CR, CRh) on day 28.

Bioequivalence Examine of Cyclosporine 100mg Capsule Below Fasting Situation

 

Complete 36 regular wholesome grownup male topics shall be enrolled within the examine.

Topics shall be administered both the Take a look at or the Reference Product with 240 mL of water in every interval as per the randomization schedule.

Topics will quick for no less than 10 hours previous to dose administration and for no less than Four hours publish dose.

Standardized meals shall be supplied in every examine interval. Water is not going to be accessible to the themes 1 hour Predose and a pair of hours Publish dose in every interval.

A complete of 24 blood samples shall be withdrawn for pharmacokinetic profiling.

The entire blood concentrations of Cyclosporine shall be measured by a validated LC/MS/MS analytical methodology.

Ratio evaluation shall be carried out for untransformed and log remodeled pharmacokinetic parameters Cmax, AUC0-72, AUC0 inf.

ANOVA shall be carried out on log remodeled pharmacokinetic parameters Cmax, AUC0-72, AUC0-inf and 90% confidence interval shall be constructed for the ratio of geometric least sq. imply of the Take a look at and Reference merchandise, obtained from the log-transformed information.

 

Bioequivalence shall be concluded if the ratio estimate in addition to its 90% confidence interval, each falls throughout the acceptable vary of 80.00% to 125.00% for Cmax, AUC0-72 and AUC0-info.

 

 

Alpha-Bungarotoxin, CF®640R, 500 ug

9-00004
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

00004-1 EA
EUR 527

Alpha-Bungarotoxin, CF®640R 100ug

9-00004
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

9-00005
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

00005-1 EA
EUR 527

Alpha-Bungarotoxin CF®488A 100ug

9-00005
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

9-00006
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

00006-1 EA
EUR 527

Alpha-Bungarotoxin, CF®568 100ug

9-00006
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

9-00007
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

00007-1 EA
EUR 527

Alpha-Bungarotoxin CF®594 100ug

9-00007
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

9-00009
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

00009-1 EA
EUR 527

Alpha-Bungarotoxin, CF®633 100ug

9-00009
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

00010-1 1MG
EUR 193
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

00010-1-1 EA
EUR 193

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011 500uG
EUR 376
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011-1 EA
EUR 376

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012 500uG
EUR 394
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012-1 EA
EUR 394

Fluorescein-alpha-bungarotoxin, 10x50ug

00013 10ST
EUR 436
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-alpha-bungarotoxin, 10x50ug

00013-1 EA
EUR 436

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014 10ST
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015 500uG
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016 10ST
EUR 560
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016-1 EA
EUR 560

Biotin-XX-A-Bungarotoxin, 500 ug

00017 500uG
EUR 455
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Biotin-XX-A-Bungarotoxin, 500 ug

00017-1 EA
EUR 455

Alpha-Bungarotoxin, CF®555, 500 ug

9-00018
  • Ask for price
  • Ask for price
  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®555, 500 ug

00018-1 EA
EUR 527

Alpha-Bungarotoxin, CF®555 100ug

9-00018
  • Ask for price
  • Ask for price
  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Acrylamide, Chemzymes Ultra Pure®

00019-100 100g
EUR 91
Description: 79-06-1

Acrylamide, Chemzymes Ultra Pure®

00019-500 500g
EUR 241
Description: 79-06-1

Biotin-cAMP, 1 mg

00020 1MG
EUR 298
Description: N/A

Biotin-cAMP, 1 mg

00020-1 20ST
EUR 298
Description: N/A

Biotin-cAMP, 50 ug

00020-1-1 EA
EUR 414

Biotin-cGMP, 1 mg

00021 1MG
EUR 331
Description: N/A

Biotin-cGMP, 1 mg

00021-1 20ST
EUR 331
Description: N/A

Biotin-cGMP, 20x50 ug

00021-1-1 EA
EUR 447

Cyanine 644-cAMP, 1 mg

00022 1MG
EUR 496
Description: N/A

Cyanine 644-cAMP, 1 mg

00022-1 20ST
EUR 496
Description: N/A

Cyanine 644-cAMP, 20x50 ug

00022-1-1 EA
EUR 647

Fluorescein Methotrexate, Triammonium Salt, 1 mg

00023 1MG
EUR 285
Description: N/A

Fluorescein Methotrexate, Triammonium Salt, 1 mg

00023-1 EA
EUR 285

Staurosporine

00025 100uG
EUR 100
Description: N/A

Staurosporine

00025-1 EA
EUR 100

Alpha-Bungarotoxin, CF®543, 500 ug

00026 500uG
EUR 527
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®543, 500 ug

00026-1 EA
EUR 527

Alpha-Bungarotoxin, CF®543, 100 ug

00026-100ug 1UG
EUR 132
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Rhodamine Phalloidin 300U

00027 300
EUR 364
Description: N/A

Rhodamine Phalloidin 300U

00027-1 EA
EUR 364

Biotin-XX-Phalloidin

00028 100U
EUR 466
Description: N/A

Biotin-XX-Phalloidin

00028-1 EA
EUR 466

Fluorescein-Phalloidin

00030 300U
EUR 364
Description: N/A

Fluorescein-Phalloidin

00030-1 EA
EUR 364

Rhodamine 110 Phalloidin

00032 300ST
EUR 364
Description: N/A

Rhodamine 110 Phalloidin

00032-1 EA
EUR 364

Sulforhodamine 101 (Texas Red®) Phalloidin

00033 300EU
EUR 364
Description: N/A

Sulforhodamine 101 (Texas Red®) Phalloidin

00033-1 EA
EUR 364

Phalloidin, CF®405M

00034 300U
EUR 482
Description: N/A

Phalloidin, CF®405M

00034-1 EA
EUR 482

Phalloidin, CF®405M

00034-T 50U
EUR 101
Description: N/A

Phalloidin, CF®405M

00034-T-1 EA
EUR 101

CF®488A-cAMP

00036 100ug
EUR 136
Description: N/A

CF®488A-cAMP

00036-1 EA
EUR 136

CF®640R-cAMP

00037 100ug
EUR 136
Description: N/A

CF®640R-cAMP

00037-1 EA
EUR 136

Phalloidin, CF555

00040 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF555

00040-T 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF®647, 300 U

00041 300U
EUR 482
Description: N/A

Phalloidin, CF®647, 300 U

00041-1 EA
EUR 482

Phalloidin, CF®647, 50 U

00041-T 50U
EUR 101
Description: N/A

Phalloidin, CF®647, 50 U

00041-T-1 EA
EUR 101

Phalloidin, CF®488A, 300 U

00042 300U
EUR 482
Description: N/A

Phalloidin, CF®488A, 300 U

00042-1 EA
EUR 482

Phalloidin, CF®488A, 50 U

00042-T 50U
EUR 101
Description: N/A

Phalloidin, CF®488A, 50 U

00042-T-1 EA
EUR 101

Phalloidin, CF®543, 300 U

00043 300U
EUR 482
Description: N/A



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