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Superior Glycation Finish Merchandise Are Related With Diabetic Macular Edema

This was a cross-sectional examine was carried out within the Hacettepe College Hospital, Division of Ophthalmology, between July 2018 and February 2019.

Whereas benefiting from the outcomes of the earlier research, the pattern measurement of the analysis was kind 1 error stage α = 0.05 and sort 2 stage β = 0.20.

The facility evaluation was statistically calculated utilizing NCCS PAS 11 program. The current examine was carried out with 90 sufferers: 50 case-patients (DM with DME) and 40 management sufferers (DM with out DME).

Excluded from the examine had been these below the age of 18 years, with no analysis of Kind 2 DM, with none anti-diabetic agent, with any illness apart from DME and DR which will have an effect on the retina, with any illness which will have an effect on the retina for the management group, with corneal, lens or vitreous opacification stopping Optical coherence tomography (OCT) withdrawal, with any systemic illness apart from DM and hypertension, with a historical past of eye surgical procedure, and with blindness or an infection within the eye, together with these lately recognized with diabetes (<1 yr) and people with particular diets.

 

 

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MC Cellufine PB

202-51 5 x 1 ml
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PB 28 dihydrochloride

B7107-10 10 mg
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PB 28 dihydrochloride

B7107-50 50 mg
EUR 1038

PB Cadherin Antibody

47938-100ul 100ul
EUR 252

PB Blocking Peptide

33R-2067 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of pb antibody, catalog no. 70R-2192

PB Cadherin Blocking Peptide

20-abx162098
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

PB Cadherin Conjugated Antibody

C47938 100ul
EUR 397

electrolyte galv.o2/pb electr., 125ml

B151 ea
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Pb(II) , DNA Aptamer, Biotinylated

AD-131-B Custom Ask for price

Pb(II) , DNA Aptamer, unlabeled

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membranes+electrolyte for o2/pb electr

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Pb(II) , DNA Aptamer, FITC labeled

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Pituitary And Brain Cadherin (PB Cadherin) Antibody

20-abx133389
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

PB-CMV-GreenPuro Scramble Hairpin Control Vector

PBSI505-000PA-1 10 ug
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PB-CMV-MCS-EF1-Puro cDNA cloning and expression vector

PB510B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-GFP cDNA cloning and expression vector

PB511B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-RFP cDNA cloning and expression vector

PB512B-1 10 ug
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PB-CMV-MCS-EF1-GreenPuro cDNA cloning and expression vector

PB513B-1 10 ug
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PB-CMV-MCS-EF1-RedPuro cDNA Cloning and Expression Vector

PB514B-2 10 ug
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PB-EF1-MCS-IRES-GFP cDNA cloning and expression vector

PB530A-2 10 ug
EUR 702

PB-EF1-MCS-IRES-RFP cDNA Cloning and Expression Vector

PB531A-2 10 ug
EUR 702

PB-EF1-MCS-IRES-Neo cDNA cloning and expression vector

PB533A-2 10 ug
EUR 702

PB-MSCV-MCS-EF1-GreenPuro cDNA Cloning and Expression Vector

PB713B-1 10 ug
EUR 702

PB-CMV-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI505A-1 10 ug
EUR 702

PB-EF1-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI506A-1 10 ug
EUR 702

piggyBac-HR with GFP+Puro markers and TK selection [MCS1-5'PB TR-EF1?-GFP-T2A-Puro-T2A-hsvTK-pA-3' PB TR-MCS2] for Gene Correction

PBHR100A-1 10 ug
EUR 1334

PB-Cuo-miR-302/367-IRES-GFP-EF1-CymR-Puro Inducible iPSC Vector

PBQM-MIR302 10 ug
EUR 2022

PB-EF1a-Oct4-Sox2-Klf4-Myc-IRES-GFP Human 4-in-1 iPSC Vector

PB630A-1 10 ug
EUR 1674

PB-Cuo-MCS-IRES-GFP-EF1-CymR-Puro Inducible cDNA Cloning and Expression Vector

PBQM812A-1 10 ug
EUR 1096

PB-Cuo-shMCS-IRES-GFP-EF1-CymR-Puro Inducible shRNA Cloning and Expression Vector

PBQMSH812A-1 10 ug
EUR 1096

Anti-Hu CD15 Pacific Blue

PB-138-T025 25 tests
EUR 154

Anti-Hu CD15 Pacific Blue

PB-138-T100 100 tests
EUR 269

Anti-Hu CD45 Pacific Blue

PB-160-T100 100 tests
EUR 269

Anti-Hu CD193 Pacific Blue

PB-161-T100 100 tests
EUR 269

Anti-Hu CD3 Pacific Blue

PB-202-T025 25 tests
EUR 154

Anti-Hu CD3 Pacific Blue

PB-202-T100 100 tests
EUR 269

Anti-Hu CD6 Pacific Blue

PB-205-T025 25 tests
EUR 154

Anti-Hu CD6 Pacific Blue

PB-205-T100 100 tests
EUR 269

Anti-Hu CD7 Pacific Blue

PB-206-T025 25 tests
EUR 154

Anti-Hu CD7 Pacific Blue

PB-206-T100 100 tests
EUR 269

Anti-Hu CD8 Pacific Blue

PB-207-T025 25 tests
EUR 154

Anti-Hu CD8 Pacific Blue

PB-207-T100 100 tests
EUR 269

Anti-Hu CD9 Pacific Blue

PB-208-T025 25 tests
EUR 154

Anti-Hu CD9 Pacific Blue

PB-208-T100 100 tests
EUR 269

Anti-Hu CD10 Pacific Blue

PB-209-T025 25 tests
EUR 154

Anti-Hu CD10 Pacific Blue

PB-209-T100 100 tests
EUR 269

Anti-Hu CD15 Pacific Blue

PB-213-T025 25 tests
EUR 154

Anti-Hu CD15 Pacific Blue

PB-213-T100 100 tests
EUR 269

Anti-Hu CD25 Pacific Blue

PB-218-T025 25 tests
EUR 154

Anti-Hu CD25 Pacific Blue

PB-218-T100 100 tests
EUR 269

Anti-Hu CD29 Pacific Blue

PB-219-T025 25 tests
EUR 154

Anti-Hu CD29 Pacific Blue

PB-219-T100 100 tests
EUR 269

Anti-Hu CD43 Pacific Blue

PB-220-T025 25 tests
EUR 154

Anti-Hu CD43 Pacific Blue

PB-220-T100 100 tests
EUR 269

Anti-Hu CD44 Pacific Blue

PB-221-T025 25 tests
EUR 154

Anti-Hu CD44 Pacific Blue

PB-221-T100 100 tests
EUR 269

Anti-Hu CD45 Pacific Blue

PB-222-T025 25 tests
EUR 154

Anti-Hu CD45 Pacific Blue

PB-222-T100 100 tests
EUR 269

Anti-Hu CD45RA Pacific Blue

PB-223-T025 25 tests
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Anti-Hu CD45RA Pacific Blue

PB-223-T100 100 tests
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Anti-Hu CD47 Pacific Blue

PB-225-T025 25 tests
EUR 154

Anti-Hu CD47 Pacific Blue

PB-225-T100 100 tests
EUR 269

Anti-Hu CD48 Pacific Blue

PB-226-T025 25 tests
EUR 154

Anti-Hu CD48 Pacific Blue

PB-226-T100 100 tests
EUR 269

Anti-Hu CD53 Pacific Blue

PB-227-T025 25 tests
EUR 154

Anti-Hu CD53 Pacific Blue

PB-227-T100 100 tests
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Anti-Hu CD59 Pacific Blue

PB-233-T025 25 tests
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Anti-Hu CD59 Pacific Blue

PB-233-T100 100 tests
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Anti-Hu CD71 Pacific Blue

PB-235-T025 25 tests
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Anti-Hu CD71 Pacific Blue

PB-235-T100 100 tests
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Anti-Hu CD31 Pacific Blue

PB-273-T025 25 tests
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Anti-Hu CD31 Pacific Blue

PB-273-T100 100 tests
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Anti-Hu CD80 Pacific Blue

PB-287-T025 25 tests
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Anti-Hu CD80 Pacific Blue

PB-287-T100 100 tests
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Anti-Hu CD14 Pacific Blue

PB-293-T025 25 tests
EUR 154

Anti-Hu CD14 Pacific Blue

PB-293-T100 100 tests
EUR 269

Anti-HLA-DR/DP Pacific Blue

PB-296-T025 25 tests
EUR 154

Anti-HLA-DR/DP Pacific Blue

PB-296-T100 100 tests
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Anti-Hu CD34 Pacific Blue

PB-297-T025 25 tests
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This the examine was carried out in accordance with the Declaration of Helsinki Moral Rules.

OCT withdrawals and CFT evaluations of these included within the examine had been made by the physician and directed to the dietician (researcher).

Demographic knowledge and the dietary habits had been collected by standardized face-to-face interviewer-assisted questionnaires.

The body weight and top of sufferers had been measured utilizing a calibrated physique composition analyser and weight scales by researcher.

BMI was evaluated based mostly on the WHO classification. Waist and hip circumference was additionally measured and evaluated when it comes to excessive threat of growing continual illnesses.

Speculation: If the waist/hip ratio is ≥0.85 for ladies and ≥0.90 for males, the danger of growing continual illnesses will increase.

Diabetic macular edema (DME) Examination After an in depth systemic and ophthalmological historical past was taken from all topics by the physician, the best-corrected visible acuity stage was measured utilizing an ETDRS chart.

A fundus examination was carried out with a 90 D lens after anterior phase examination and pupil dilation with a biomicroscope.

A spectral-domain OCT (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany) was utilized for the analysis of CFT.

After a minimal of eight hours of fasting, roughly 5 ml of peripheral venous blood was collected from the antecubital area within the HÜTF Ophthalmology Clinic between 08:00 and 10:00.

Evaluation of dietary consumption and dietary AGEs The dietary consumption of contributors was assessed utilizing a validated quantitative meals frequency questionnaire (QFFQ) (together with about 110 meals gadgets take 20-25 minutes to finish).

Meals had been categorized into eight classes: dairy merchandise, meat merchandise, fruits, greens, bread and cereals, drinks, and desserts. Additionally, questions had been requested to sufferers about conventional cooking strategies to calculate dietary AGE intakes.

Corresponding to what cooking strategies do they cook dinner the meals? How lengthy do they cook dinner the meals?

Standardized meals recipes for Turkey and the Vitamin Data System (BEBIS) program had been used to calculate the common each day vitality and nutrient consumption for every participant.

In the meantime, to evaluate dietary AGEs from the QFFQ, every meals’s contribution to dAGEs consumption was calculated based mostly on the Advance Glycation Finish Merchandise in Meals Desk printed by the Uribarri et al., which includes knowledge on 549fooditems.

Pattern Assortment and Evaluation The serum samples collected in the course of the analysis had been delivered to the laboratory whereas preserving the chilly chain. The enzyme-labeled immune “Enzyme-Linked Immunosorbent Assay (ELISA)” check was carried out with biologists of the corporate utilizing a Biotek 800TS gadget.

Whereas analyzing the samples, Human CML Elisa Package 96 checks for serum AGE and Human RAGE Elisa Package 96 check kits for serum RAGE had been used. Carboxymethyl lysine (CML) was thought of because the AGE parameter, being probably the most simply detected and probably the most plentiful kind of AGE in people.

The minimumdetectable dose of CML in people is usually lower than 15.6 pg/ml

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MC Cellufine PB

202-15 1 x 5 ml
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MC Cellufine PB

202-51 5 x 1 ml
EUR 452

PB 28 dihydrochloride

B7107-10 10 mg
EUR 284

PB 28 dihydrochloride

B7107-50 50 mg
EUR 1038

PB Cadherin Antibody

47938-100ul 100ul
EUR 252

PB Blocking Peptide

33R-2067 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of pb antibody, catalog no. 70R-2192

PB Cadherin Blocking Peptide

20-abx162098
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

PB Cadherin Conjugated Antibody

C47938 100ul
EUR 397

electrolyte galv.o2/pb electr., 125ml

B151 ea
EUR 48

Pb(II) , DNA Aptamer, Biotinylated

AD-131-B Custom Ask for price

Pb(II) , DNA Aptamer, unlabeled

AD-131-U Custom Ask for price

membranes+electrolyte for o2/pb electr

SZ02K ea
EUR 138

Pb(II) , DNA Aptamer, FITC labeled

AD-131-F Custom Ask for price

Pituitary And Brain Cadherin (PB Cadherin) Antibody

20-abx133389
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

PB-CMV-GreenPuro Scramble Hairpin Control Vector

PBSI505-000PA-1 10 ug
EUR 689

PB-CMV-MCS-EF1-Puro cDNA cloning and expression vector

PB510B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-GFP cDNA cloning and expression vector

PB511B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-RFP cDNA cloning and expression vector

PB512B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-GreenPuro cDNA cloning and expression vector

PB513B-1 10 ug
EUR 702

PB-CMV-MCS-EF1-RedPuro cDNA Cloning and Expression Vector

PB514B-2 10 ug
EUR 702

PB-EF1-MCS-IRES-GFP cDNA cloning and expression vector

PB530A-2 10 ug
EUR 702

PB-EF1-MCS-IRES-RFP cDNA Cloning and Expression Vector

PB531A-2 10 ug
EUR 702

PB-EF1-MCS-IRES-Neo cDNA cloning and expression vector

PB533A-2 10 ug
EUR 702

PB-MSCV-MCS-EF1-GreenPuro cDNA Cloning and Expression Vector

PB713B-1 10 ug
EUR 702

PB-CMV-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI505A-1 10 ug
EUR 702

PB-EF1-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI506A-1 10 ug
EUR 702

piggyBac-HR with GFP+Puro markers and TK selection [MCS1-5'PB TR-EF1?-GFP-T2A-Puro-T2A-hsvTK-pA-3' PB TR-MCS2] for Gene Correction

PBHR100A-1 10 ug
EUR 1334

PB-Cuo-miR-302/367-IRES-GFP-EF1-CymR-Puro Inducible iPSC Vector

PBQM-MIR302 10 ug
EUR 2022

PB-EF1a-Oct4-Sox2-Klf4-Myc-IRES-GFP Human 4-in-1 iPSC Vector

PB630A-1 10 ug
EUR 1674

PB-Cuo-MCS-IRES-GFP-EF1-CymR-Puro Inducible cDNA Cloning and Expression Vector

PBQM812A-1 10 ug
EUR 1096

PB-Cuo-shMCS-IRES-GFP-EF1-CymR-Puro Inducible shRNA Cloning and Expression Vector

PBQMSH812A-1 10 ug
EUR 1096

Anti-Hu CD15 Pacific Blue

PB-138-T025 25 tests
EUR 154

Anti-Hu CD15 Pacific Blue

PB-138-T100 100 tests
EUR 269

Anti-Hu CD45 Pacific Blue

PB-160-T100 100 tests
EUR 269

Anti-Hu CD193 Pacific Blue

PB-161-T100 100 tests
EUR 269

Anti-Hu CD3 Pacific Blue

PB-202-T025 25 tests
EUR 154

Anti-Hu CD3 Pacific Blue

PB-202-T100 100 tests
EUR 269

Anti-Hu CD6 Pacific Blue

PB-205-T025 25 tests
EUR 154

Anti-Hu CD6 Pacific Blue

PB-205-T100 100 tests
EUR 269

Anti-Hu CD7 Pacific Blue

PB-206-T025 25 tests
EUR 154

Anti-Hu CD7 Pacific Blue

PB-206-T100 100 tests
EUR 269

Anti-Hu CD8 Pacific Blue

PB-207-T025 25 tests
EUR 154

Anti-Hu CD8 Pacific Blue

PB-207-T100 100 tests
EUR 269

Anti-Hu CD9 Pacific Blue

PB-208-T025 25 tests
EUR 154

Anti-Hu CD9 Pacific Blue

PB-208-T100 100 tests
EUR 269

Anti-Hu CD10 Pacific Blue

PB-209-T025 25 tests
EUR 154

Anti-Hu CD10 Pacific Blue

PB-209-T100 100 tests
EUR 269

Anti-Hu CD15 Pacific Blue

PB-213-T025 25 tests
EUR 154

Anti-Hu CD15 Pacific Blue

PB-213-T100 100 tests
EUR 269

Anti-Hu CD25 Pacific Blue

PB-218-T025 25 tests
EUR 154

Anti-Hu CD25 Pacific Blue

PB-218-T100 100 tests
EUR 269

Anti-Hu CD29 Pacific Blue

PB-219-T025 25 tests
EUR 154

Anti-Hu CD29 Pacific Blue

PB-219-T100 100 tests
EUR 269

Anti-Hu CD43 Pacific Blue

PB-220-T025 25 tests
EUR 154

Anti-Hu CD43 Pacific Blue

PB-220-T100 100 tests
EUR 269

Anti-Hu CD44 Pacific Blue

PB-221-T025 25 tests
EUR 154

Anti-Hu CD44 Pacific Blue

PB-221-T100 100 tests
EUR 269

Anti-Hu CD45 Pacific Blue

PB-222-T025 25 tests
EUR 154

Anti-Hu CD45 Pacific Blue

PB-222-T100 100 tests
EUR 269

Anti-Hu CD45RA Pacific Blue

PB-223-T025 25 tests
EUR 154

Anti-Hu CD45RA Pacific Blue

PB-223-T100 100 tests
EUR 269

Anti-Hu CD47 Pacific Blue

PB-225-T025 25 tests
EUR 154

Anti-Hu CD47 Pacific Blue

PB-225-T100 100 tests
EUR 269

Anti-Hu CD48 Pacific Blue

PB-226-T025 25 tests
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Anti-Hu CD48 Pacific Blue

PB-226-T100 100 tests
EUR 269

Anti-Hu CD53 Pacific Blue

PB-227-T025 25 tests
EUR 154

Anti-Hu CD53 Pacific Blue

PB-227-T100 100 tests
EUR 269

Anti-Hu CD59 Pacific Blue

PB-233-T025 25 tests
EUR 154

Anti-Hu CD59 Pacific Blue

PB-233-T100 100 tests
EUR 269

Anti-Hu CD71 Pacific Blue

PB-235-T025 25 tests
EUR 154

Anti-Hu CD71 Pacific Blue

PB-235-T100 100 tests
EUR 269

Anti-Hu CD31 Pacific Blue

PB-273-T025 25 tests
EUR 154

Anti-Hu CD31 Pacific Blue

PB-273-T100 100 tests
EUR 269

Anti-Hu CD80 Pacific Blue

PB-287-T025 25 tests
EUR 154

Anti-Hu CD80 Pacific Blue

PB-287-T100 100 tests
EUR 269

Anti-Hu CD14 Pacific Blue

PB-293-T025 25 tests
EUR 154

Anti-Hu CD14 Pacific Blue

PB-293-T100 100 tests
EUR 269

Anti-HLA-DR/DP Pacific Blue

PB-296-T025 25 tests
EUR 154

Anti-HLA-DR/DP Pacific Blue

PB-296-T100 100 tests
EUR 269

Anti-Hu CD34 Pacific Blue

PB-297-T025 25 tests
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Anti-Hu CD34 Pacific Blue

PB-297-T100 100 tests
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Anti-Hu CD105 Pacific Blue

PB-298-T025 25 tests
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Anti-Hu CD105 Pacific Blue

PB-298-T100 100 tests
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Anti-Hu CD19 Pacific Blue

PB-305-T025 25 tests
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Anti-Hu CD19 Pacific Blue

PB-305-T100 100 tests
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Anti-Hu CD21 Pacific Blue

PB-306-T025 25 tests
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Anti-Hu CD21 Pacific Blue

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Anti-Hu CD27 Pacific Blue

PB-308-T025 25 tests
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Anti-Hu CD27 Pacific Blue

PB-308-T100 100 tests
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Anti-Hu CD41 Pacific Blue

PB-309-T025 25 tests
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Anti-Hu CD41 Pacific Blue

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Anti-Hu CD177 Pacific Blue

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Anti-Hu IgM Pacific Blue

PB-320-C100 0.1 mg
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